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Carprofen Chewable Tablets, Packaging Size: 4 Tab Per Box, Prescription

Carprofen Chewable Tablets, Packaging Size: 4 Tab Per Box, Prescription

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₹ 705 / Piece

by: Amigoz Lifesciences, Vadodara

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Product Specifications
Packaging Size
4 tab per box
Osteoarthritis and other musculo-skeletal disorders,pre and post- orthopaedic surgery and Trauma
Prescription/Non prescription
Packaging Type
4tab per box
Manufacture By
Veterinary. Not for human use. For treatment of animals only
75 mg
Non steroidal anti - inflammatory drug for Oral use in dogs only.
Packing Size
1 x 4 Tablets
Country of Origin
Made in India
Minimum Order Quantity
3 Piece

Product Description

Carprofen chewable tablets-25 mg 
CATEGORY: Non – steroidal anti-inflammatory drug
For oral use in dogs only 
DESCRIPTION: Carodyl (carprofen) is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that includes ibuprofen, naproxen and ketoprofen. Carprofen is the nonproprietary designation for a substituted carbazole, 6-chloro-α-methyl-9H-carbazole-2-acetic acid. 
Carprofen is a non-narcotic, non-steroidal anti-inflammatory agent with characteristic analgesic and antipyretic activity approximately equipotent to indomethacin in animal models.1
The mechanism of action of carprofen, like that of other NSAIDs, is believed to be associated with the inhibition of cyclooxygenase activity. Two unique cyclooxygenases have been described in mammals. The constitutive cyclooxygenase, COX-1, synthesizes prostaglandins necessary for normal gastrointestinal and renal function. The inducible cyclooxygenase, COX-2, generates prostaglandins involved in inflammation. Inhibition of COX-1 is thought to be associated with gastrointestinal and renal toxicity while inhibition of COX-2 provides anti-inflammatory activity. The specificity of a particular NSAID for COX-2 versus COX-1 may vary from species to species. Carprofen has also been shown to inhibit the release of several prostaglandins in two inflammatory cell systems: rat polymorphonuclear leukocytes (PMN) and human rheumatoid synovial cells, indicating inhibition of acute (PMN system) and chronic (synovial cell system) inflammatory reactions.
Several studies have reported that carprofen has modulatory effects on both humoral and cellular immune responses. Data also indicate that carprofen inhibits the production of osteoclast-activating factor (OAF), PGE1, and PGE2 by its inhibitory effect in prostaglandin biosynthesis.
Peak blood plasma concentrations are achieved in 1-3 hours after oral administration of 1, 5, and 25 mg/kg to dogs. The mean terminal half-life of carprofen is approximately 8 hours (range 4.5-9.8 hours) after single oral doses varying from 1-35 mg/kg of body weight. After a 100 mg single intravenous bolus dose, the mean elimination half-life was approximately 11.7 hours in the dog. Carprofen is more than 99% bound to plasma protein and exhibits a very small volume of distribution.
Carprofen is eliminated in the dog primarily by biotransformation in the liver followed by rapid excretion of the resulting metabolites (the ester glucuronide of carprofen and the ether glucuronides of 2 phenolic metabolites, 7-hydroxy carprofen and 8-hydroxy carprofen) in the feces (70-80%) and urine (10-20%). Some enterohepatic circulation of the drug is observed.
INDICATIONS: Carodyl is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
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Company Information

Amigoz Lifesciences
Vadodara, Gujarat
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Carprofen Chewable Tablets, Packaging Size: 4 Tab Per Box, Prescription

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Carprofen Chewable Tablets
by:Amigoz Lifesciences, Vadodara

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Carprofen Chewable Tablets, Packaging Size: 4 Tab Per Box, Prescription