Hydroxycarbamide is used for the following indications:
Myeloproliferative disease (primarily polycythemia vera and essential thrombocytosis). It has been found to be superior to anagrelide for the control of ET.
Sickle-cell disease
AIDS as an adjunct to ddI in combination antiretroviral therapies
Second line treatment for psoriasis
Systemic mastocytosis
Chronic myelogenous leukemia (largely replaced by imatinib, but still in use for its cost-effectiveness)[8]