Vidagliptin + Metformin Tablet 50mg+1000mg

Vildagliptin 50 mg + Metformin 1000 mg Tablet is a dual-combination oral medication for the effective management of Type 2 Diabetes Mellitus. This tablet is typically prescribed when blood sugar levels are not adequately controlled by diet, exercise, or monotherapy. It combines two complementary antidiabetic agents:

1. Vildagliptin (DPP-4 Inhibitor / Gliptin): This component works by inhibiting the enzyme Dipeptidyl Peptidase-4 (DPP-4). By doing so, it enhances the levels of naturally occurring incretin hormones (like GLP-1 and GIP). These hormones increase glucose-dependent insulin secretion from the pancreas and reduce glucagon secretion, leading to better control of both fasting and post-meal blood sugar levels.

2. Metformin (Biguanide): This component primarily acts by:

   • Reducing the amount of glucose produced by the liver.
   • Decreasing the absorption of glucose from the intestines.
   • Improving the body's sensitivity to insulin, allowing cells to utilize glucose more efficiently.

This combination provides a comprehensive approach to diabetes management by improving both insulin release and the body's response to insulin, without typically causing weight gain.

Key Features:

• Dual-Action Formula: Combines two distinct mechanisms for robust blood glucose control.
• Glucose-Dependent Insulin Release: Vildagliptin stimulates insulin only when blood sugar is high, reducing hypoglycemia risk.
• Improved Insulin Sensitivity: Metformin component enhances the body's use of insulin.
• Convenient Dosing: Fixed-dose combination simplifies medication regimen.
• Weight Neutrality: Generally does not cause weight gain.
• Quality Assured: Manufactured in WHO-GMP certified facilities.

Composition (per tablet):

• Vildagliptin IP: 50 mg
• Metformin Hydrochloride IP: 1000 mg
• Excipients: q.s.

Indications:

• Type 2 Diabetes Mellitus: Indicated as an adjunct to diet and exercise in adult patients whose blood glucose levels are not adequately controlled with metformin or vildagliptin monotherapy, or who are already being treated with both medications separately. It can also be used in combination with other diabetes medicines, including insulin.