Zurzuvae (zuranolone) is a prescription oral medication in capsule form used to treat adults with postpartum depression (PPD). It is a 14-day, once-daily treatment that works by enhancing the function of the brain's major inhibitory neurotransmitter, GABA. Patients should avoid driving or hazardous activities for at least 12 hours after each dose due to potential side effects like sleepiness and dizziness